Shiga toxin causes hemorrhagic colitis and hemolytic-uremic syndrome by damaging endothelial cells in the microvasculature of the colon and the glomeruli, respectively. Dysentery is caused when the bacteria escape the epithelial cell phagolysosome, multiply within the cytoplasm, and destroy host cells. Shigella bacteria invade the intestinal mucosal cells but do not usually go beyond the lamina propria. Transmission is fecal-oral and is remarkable for the small number of organisms that may cause disease (10 ingested organisms cause illness in 10% of volunteers, and 500 organisms cause disease in 50% of volunteers).
JSTOR ( July 2018) ( Learn how and when to remove this template message).Unsourced material may be challenged and removed.įind sources: "Bacillary dysentery" – news Please help improve this article by adding citations to reliable sources. This Section needs additional citations for verification. One characteristic of bacillary dysentery is blood in stool, which is the result of invasion of the mucosa by the pathogen.
īacillary dysentery should not be confused with diarrhea caused by other bacterial infections. It is sometimes listed as an explicit differential diagnosis of bacillary dysentery, as opposed to a cause. Salmonellosis caused by Salmonella enterica (serovar Typhimurium) has also been described as a cause of bacillary dysentery, though this definition is less common. A study in China indicated that Shigella flexneri 2a was the most common serotype. Three species are associated with bacillary dysentery: Shigella sonnei, Shigella flexneri and Shigella dysenteriae. Shigellosis is caused by one of several types of Shigella bacteria. The term is usually restricted to Shigella infections. Bacillary dysentery is a type of dysentery, and is a severe form of shigellosis.īacillary dysentery is associated with species of bacteria from the family Enterobacteriaceae.
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